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龋病是慢性感染性疾病,是口腔内多种微生物共同作用的结果。龋病相关微生物在龋病病理变化中的作用,主要取决于三大生物学特性:产酸与耐酸力、产糖能力和黏附能力。随着近年来龋病研究的日益深入,龋病相关分子机制逐渐引起学者们的重视,越来越多的微生物也被认为与龋病相关。现对主要龋病相关微生物的致龋性进行综述,以期对龋病的深入研究提供参考。
Caries is a chronic infectious disease that results from the combined action of multiple microorganisms in the mouth. The role of cariogenic microorganisms in the pathological changes of dental caries mainly depends on the three biological characteristics: acid production and acid resistance, sugar production capacity and adhesion. With the deepening of research on dental caries in recent years, molecular mechanisms related to dental caries gradually attracted the attention of scholars, and more and more microorganisms are also considered to be associated with dental caries. The cariogenicity of the major cariogenic microorganisms is reviewed in order to provide reference for the further study of dental caries.