带瘤动物血清能抑制小鼠脾细胞抗绵羊红细胞的空斑形成细胞反应(PFC),说明其血清中存在免疫抑制因子。1980年Takateru等报道用肺癌血清作PFC免疫抑制试验,阳性率达78％,非癌肺部疾病者为6％,正常人为7％,并提出有可能将此法用于肺癌的免疫诊断。由于此免疫抑制试验的结果与肺癌的组织分型无显著关系,提示可用于其他肿瘤的测定。我们尝试用胃癌血清作PGC免疫抑制试验,以了解,胃癌血清的免疫抑制活性,现将结果简要报道如下。 材料与方法 取C57BL/6J小鼠,每组3只。将0.4ml经56℃ Tumor-bearing animal serum can inhibit mouse spleen cells against plaque-forming erythrocyte response (PFC), indicating that the serum immunosuppressive factor. In 1980, Takateru et al. Reported that PFC immunosuppression test with lung cancer serum had a positive rate of 78%, non-cancerous lung disease was 6% and normal rate was 7%. It was also proposed that this method could be used for immune diagnosis of lung cancer. Because the results of this immunosuppression test and lung cancer tissue type no significant relationship, suggesting that other tumors can be used for the determination. We tried gastric cancer serum PGC immunosuppression test to understand the gastric cancer serum immunosuppressive activity, the results are now briefly reported as follows. Materials and Methods C57BL / 6J mice were used in this study. 0.4 ml at 56 ° C