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本文报告山苍子油的平喘与抗过敏药理研究结果。山苍子油能松弛豚鼠离体气管平滑肌,增加豚鼠离体肺灌流量。对豚鼠因吸入致痉剂所致药物性哮喘有明显保护作用。对大鼠被动皮肤过敏反应(PCA)有抑制作用。能保护豚鼠过敏性休克和抑制豚鼠离体回肠过敏性收缩。对慢反应物质(SRS-A)引致豚鼠离体回肠收缩有阻断和拮抗作用。山苍子油上述药理作用为其对慢性支气管炎的良好疗效提供了依据。
This article reports the results of anti-asthmatic and anti-allergy pharmacological research of Litsea cubeba oil. Litsea cubeba oil can relax guinea pig tracheal smooth muscle, increased guinea pig isolated lung perfusion. On guinea pig due to inhaled spasm agent caused by drug-induced asthma with significant protective effect. Rat passive skin allergy (PCA) inhibition. Can protect guinea pig anaphylactic shock and inhibit guinea pig ileal anaphylactic contraction. Slow and reactive substances (SRS-A) induced guinea pig ileum contraction in vitro blocking and antagonistic effect. The above pharmacological effects of Litsea Cubeba oil provides the basis for its good curative effect on chronic bronchitis.