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目的 探讨巨大垂体腺瘤术后水钠紊乱的临床特点及治疗方法。方法 术前、手术当日及术后每日定时进行电解质检测并记录每小时尿量 ,根据其变化进行治疗。结果 5 6例巨大垂体腺瘤中 15例出现尿崩症 ,其中有 8例 1周内恢复 ,5例 2周内恢复 ,2例 4周内恢复 ;16例术后出现血钠紊乱 ,其中 ,9例 2周内恢复 ,5例 4周内恢复 ,另 2例 2个月内恢复。结论 巨大垂体腺瘤术后水钠紊乱情况复杂。术后尿崩症绝大多数病人可在术后早期得到恢复 ;术后应根据水钠的检测水平进行相应的治疗
Objective To investigate the clinical features and treatment of water-sodium disorders after huge pituitary adenoma. Methods Electrolyte testing was performed before surgery, on the day of operation, and daily after operation. The urine output was recorded every hour, and the changes were followed up. Results Fifty-five patients with giant pituitary adenomas had diabetes insipidus. Among them, 8 patients recovered within 1 week, 5 patients recovered within 2 weeks, 2 patients recovered within 4 weeks and 16 patients presented with disorder of serum sodium. Among them, 9 cases recovered within 2 weeks, 5 cases recovered within 4 weeks and the other 2 cases recovered within 2 months. Conclusion The huge hydrops and pituitary adenomas have complicated water and sodium disorders. The vast majority of patients with postoperative diabetes insipidus can be recovered early after surgery; postoperative water and sodium should be based on the detection of the appropriate level of treatment