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目的了解肠道真菌医院感染情况及其危险因素,以便制定防控措施。方法通过回顾性调查方法,对本医院2009-2010年住院病人中肠道真菌医院感染现状进行了调查。结果在调查的2年时间内,共有住院病人48 697例,查出肠道真菌医院感染患者共计129例。从129例肠道感染患者粪便标本中检出真菌131株,其中白色念珠菌占55.73%。在本组病例中,年龄超过65岁者占48.83%,有39.53%的患者接受联合应用抗生素,且很大部分患者伴有较严重的基础病。结论肠道真菌感染主要由白色念珠菌引起,高龄患者、不合理使用抗生素和严重基础病是引发真菌感染的重要危险因素。
Objective To understand the intestinal fungal hospital infection and its risk factors in order to develop prevention and control measures. Methods The retrospective investigation method was used to investigate the prevalence of intestinal fungal nosocomial infection in inpatients from 2009 to 2010 in our hospital. Results A total of 48 697 hospitalized patients were enrolled during the 2-year survey. A total of 129 cases of intestinal fungal nosocomial infections were detected. 131 strains of fungi were detected in stool samples from 129 patients with intestinal infections, of which Candida albicans accounted for 55.73%. In this group of patients, over the age of 65 accounted for 48.83%, 39.53% of patients received combined antibiotics, and most patients with more serious underlying disease. Conclusions Intestinal fungal infections are mainly caused by Candida albicans. Older patients, unreasonable use of antibiotics and severe underlying diseases are important risk factors for causing fungal infections.