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自从1954年Wilson首次证实，针对精子抗原的自身抗体妨碍正常的生育过程以来，各国研究者做了大量的免疫试验，发现不育男子的血清和精浆中存在各种抗精子抗体（AntispermAntibodies，AsAb）［’1。普遍认为精子抗原的自身免疫反应是男性不育的主要原因之一。许多实验研究都以
Since Wilson first confirmed in 1954 that autoantibodies to sperm antigens interfere with normal fertility, researchers from various countries have done a lot of immunological tests and found that antisperm antibodies (AntispermAntibodies, AsAbs )[’1. It is generally accepted that the autoimmune response of sperm antigens is one of the major causes of male infertility. Many experimental studies have been