论文部分内容阅读
目的:调查2002—2003年我国甲真菌病致病菌流行情况。方法:在全国进行多中心开放性研究,自2002年5月—2003年11月,采用统一培养基,多点接种法进行研究。结果:从1084例患者965个培养基中分离出739株致病菌,其中皮癣菌占首位,而皮癣菌中红色毛癣菌占56.4%,须癣毛癣菌占5.5%,犬小孢子菌占0.3%,石膏样小孢子菌占2.6%,絮状表皮癣菌占1.5%,紫色毛癣菌占0.1%等;酵母菌居第2位,其中白念珠菌占10.0%,光滑念珠菌占5.1%,热带念珠菌占4.5%,近平滑念珠菌占5.8%,克柔念珠菌占1.9%等;霉菌居第3位。结论:甲真菌病致病菌中酵母菌类日益增多,故治疗应个体化,宜选用广谱抗真菌药物治疗。
Objective: To investigate the prevalence of onychomycosis in China from 2002 to 2003. METHODS: A multicenter open-label study was conducted throughout the country. From May 2002 to November 2003, studies were conducted using a uniform culture medium and a multi-point inoculation method. Results: 739 strains of pathogens were isolated from 965 mediums of 1084 patients, of which dermatophytes accounted for the first place, while Trichophyton rubrum accounted for 56.4%, Trichophyton mentagrophytes accounted for 5.5% and dogs were small Spores accounted for 0.3%, gypsum-like microspores accounted for 2.6%, Epidermophyton floccosum accounted for 1.5%, Trichophyton rubrum accounted for 0.1%; yeast ranked No. 2, Candida albicans accounted for 10.0%, smooth beads Accounting for 5.1%, Candida tropicalis accounted for 4.5%, Candida parapsilosis accounted for 5.8%, Candida krusei accounted for 1.9% and so on; mold ranks third. Conclusion: There is an increasing number of yeasts in the pathogens of onychomycosis. Therefore, treatment should be individualized and broad-spectrum antifungal agents should be used.