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目的探索健康管理短期体重干预对II型糖尿病患者体内糖脂代谢的影响。方法采用健康管理模式和自身对照流行病学研究方法,对116名超重或肥胖的II型糖尿病患者实施45天体重干预。结果与干预前比较,干预后患者空腹血糖(FBG)和餐后2h血糖水平、体重、BMI、腰围、臀围和上臂围值均有显著性下降(P<0.05);血清TC、HDL-C、LDL-C水平均有显著性升高(P<0.05);血清TG水平变化不明显。结论对II型糖尿病患者进行健康管理短期体重干预时,其血脂代谢具有特殊性。
Objective To explore the effect of short-term weight management intervention on the metabolism of glucose and lipid in type 2 diabetic patients. Methods A total of 116 overweight or obese patients with type 2 diabetes underwent 45-day weight intervention using the health management model and the self-controlled epidemiological study. Results Compared with those before intervention, the levels of fasting blood glucose (FBG) and 2h postprandial blood glucose, body mass, BMI, waist circumference, hip circumference and upper arm circumference were significantly decreased after intervention (P <0.05) , LDL-C levels were significantly increased (P <0.05); serum TG levels did not change significantly. Conclusions The lipid metabolism of patients with type 2 diabetes is very special when it is used for short-term weight management.