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目的探讨葡萄胎的病理特点,提高病理正确诊断率。方法收集本院2008年1月至2011年6月病理诊断的葡萄胎的患者标本进行病理检查。结果侵袭性葡萄胎镜下观察:肌层内查见水肿变性的胎盘绒毛组织;部分绒毛水肿变性镜下观察:部分绒毛间质水肿变性,滋养细胞轻度增生;葡萄胎可疑镜下观察:部分绒毛间质水肿变性,灶状滋养细胞增生;完全性葡萄胎镜下观察弥漫性绒毛间质水肿,间质血管减少或消失,滋养细胞轻、中、重不同程度的增生,常伴有异型性;部分性葡萄胎镜下观察:部分绒毛间质高度水肿,间质血管减少或消失,滋养细胞轻、中不同程度的增生。结论掌握葡萄胎的肉眼观察和镜下观察特点,结合临床进行分析有助于提高正确诊断率。
Objective To investigate the pathological features of hydatidiform mole and improve the correct diagnosis of pathology. Methods The specimens of patients with hydatidiform mole diagnosed in our hospital from January 2008 to June 2011 were collected for pathological examination. Results of invasive hydatidiform mole microscopic observation: intramural see edema degeneration of placental villi; partial villus edema microscope observation: part villus edema degeneration, mild dysplastic trophoblast; Mole suspicious microscopic observation: part Degeneration of villus interstitial edema, focal trophoblastic proliferation; complete hydatidiform mole microscope observation of diffuse villus interstitial edema, interstitial blood vessels decreased or disappeared, trophoblast cells of light, moderate and severe degree of proliferation, often accompanied by atypia ; Partial hydatidiform mole microscopic observation: part of the villous interstitial edema, interstitial blood vessels decreased or disappeared, trophoblast cells light, in varying degrees of proliferation. Conclusion grasping the macroscopic and microscopic observation of features, combined with clinical analysis will help to improve the correct diagnosis rate.