因为急性胰腺炎可能与其它腹内疾病的症状和体征十分相似,故需有一种诊断胰腺炎的实验室指标。血清淀粉酶的增高虽已作为这样的指标而被广泛应用,但在肾功能衰竭、消化性溃疡、胆总管结石性梗阻、肠梗阻和梗死、肝的炎症或创伤以及生殖道的炎症或肿瘤等其它情况亦会增高。在这些情况下,尿淀粉酶的测定结果大多数只不过反映血清淀粉酶的增高而已,并无其它价值。然而在急性胰腺炎,肾对淀粉酶的清除率是增加的,这可能作为鉴别诊断的一种更为灵敏的工具。为了补偿已知的和未能预料到的肾功能异常,Blainey、Levitt和Mulhausen等人提出把淀粉酶清除率用肌酐清 Because acute pancreatitis may be very similar to the symptoms and signs of other intra-abdominal disease, a laboratory marker for the diagnosis of pancreatitis is required. Although the increase of serum amylase has been widely used as such an index, it has been widely used in renal failure, peptic ulcer, common bile duct obstruction, intestinal obstruction and infarction, inflammation or trauma of the liver and genital tract inflammation or tumor Other situations will also increase. In these cases, most of the results of urinary amylase reflect only elevated serum amylase, and have no other value. However, in acute pancreatitis, renal clearance of amylase is increased, which may serve as a more sensitive tool for differential diagnosis. In order to compensate for known and unexpected renal dysfunction, Blainey, Levitt and Mulhausen et al proposed that the amylase clearance rate with creatinine