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目的评价紫杉醇与顺铂同步放化疗治疗老年食管癌的临床疗效。方法对42例老年食管癌,进行紫杉醇与顺铂同步放化疗治疗。结果 40例患者可作近期疗效评价,治疗有效率47.5%(19/40)。主要为急性放射性食管炎和Ⅲ级以上血液系统的毒副反应,经过对症治疗均可控制,无治疗引起的死亡病例。结论紫杉醇与顺铂同联合放化疗治疗老年食管癌患者是安全、有效的。
Objective To evaluate the clinical efficacy of concurrent chemoradiotherapy with cisplatin in the treatment of elderly patients with esophageal cancer. Methods Forty-two elderly patients with esophageal cancer were treated with paclitaxel and cisplatin concurrent chemoradiotherapy. Results 40 patients can be used for short-term efficacy evaluation, the effective rate was 47.5% (19/40). Mainly for acute radiation esophagitis and grade Ⅲ blood system side effects, after symptomatic treatment can be controlled, no treatment-induced deaths. Conclusion Paclitaxel and cisplatin combined with radiotherapy and chemotherapy for elderly patients with esophageal cancer is safe and effective.