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作者曾报导,人类母体血清中存在多胺氧化酶活性,从孕期10周起显著增高,在分娩72小时内降至测不出的水平。在胎盘后血清中(多取自绒毛间隙血液),此酶活性高出母体尿中或外周簿脉血中的20～30倍。人的胎盘后血清加外源精胺(Sper-mine)后,在试管内能显著抑制自然生长的人淋巴细胞对~3H-胸腺嘧啶的摄取。其抑制的程度与血清多胺氧化酶的活性成正比。在人胎盘中富含多肢。胎盘中的多胺氧化酶和多胺反应的产物,可能对淋巴细胞的增殖起抑制作用,有利于着床。自然流产和习惯流产可能有免疫
The authors have reported that there is polyamine oxidase activity in human maternal serum that is significantly increased from 10 weeks of pregnancy and falls to undetectable levels within 72 hours of delivery. In placental sera (mostly taken from villus interstitial blood), this enzyme activity is 20 to 30 times higher in maternal urine or peripheral blood albumin. Human placental sera plus exogenous spermine significantly inhibits the uptake of 3H-thymidine by human lymphocytes in vitro in vitro. The degree of inhibition is proportional to the activity of serum polyamine oxidase. Human placenta is rich in multiple limbs. Placenta polyamine oxidase and polyamine reaction products, may inhibit lymphocyte proliferation, is conducive to implantation. Natural abortion and habitual abortion may be immune