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目的探讨经皮椎体成形术(PVP)与经皮球囊扩张椎体成形术(PKP)治疗轻中度骨质疏松性椎体压缩性骨折(OVCFs)的临床疗效。方法回顾性分析48例轻中度OVCFs患者的临床资料,其中行PVP25例,PKP23例;比较两组患者手术前后Cobb’s角、椎体前缘高度、视觉模拟评分(VAS)、活动功能评分、并发症和治疗费用等情况。结果两组患者手术前后Cobb’s角、椎体前缘高度、VAS、活动功能评分比较,差异均有统计学意义(均P<0.05),其中术后3d、术后3个月和术后6个月均较术前明显好转(均P<0.05)。两组患者术后并发症比较,差异无统计学意义(P>0.05);治疗费用比较,PKP组明显高于PVP组(P<0.05)。结论PVP与PKP治疗轻中度OVCFs的临床疗效相当,从治疗成本考虑,建议优先应用PVP。
Objective To investigate the clinical efficacy of percutaneous vertebroplasty (PVP) and percutaneous balloon angioplasty (PKP) in the treatment of mild to moderate osteoporotic vertebral compression fractures (OVCFs). Methods The clinical data of 48 patients with mild to moderate OVCFs were analyzed retrospectively. Among them, 25 cases were PVP and 23 cases were PKP. Cobb’s angle, anterior vertebral height, visual analogue scale (VAS), activity score, Symptoms and treatment costs and so on. Results There were significant differences in Cobb’s angle, anterior vertebral height, VAS, functional score before and after surgery (all P <0.05), including postoperative 3d, postoperative 3 months and postoperative 6 The average monthly improvement was significantly (P <0.05). There was no significant difference in postoperative complications between the two groups (P> 0.05). The treatment cost was significantly higher in PKP group than in PVP group (P <0.05). Conclusion The clinical efficacy of PVP and PKP in the treatment of mild-to-moderate OVCFs is comparable. Given the treatment cost, it is recommended to give priority to PVP.