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笔者应用氨茶碱、654-2治疗婴儿毛细支气管炎,并观察其与常规的激素疗效比较。 1 临床资料 1995—1997年治疗婴儿毛细支气管炎80例,男52例,女28例,≤2月13例,～4月26例,～5月41例,全部病例均有不同程度的咳喘,其中58例喘憋,有紫绀,呼吸困难。32例发热。肺部听诊均闻及哮鸣音,吸气期延长。68例闻及不同程度的细湿罗音,所有病例均符合毛细支气管炎诊断标准。将80例随机分为两组。对照组40例,治疗组40例。治疗组应用抗生素,病毒唑加用氨茶碱(2～4mg·kg~(-1)/次)和654-2(0.2～0.3 mg·kg~(-1)/次)溶于0.56mol·L~(-1)葡萄糖注射液50ml中静滴,每天1～2次,6d一个疗程,对照组采用常规治疗,即抗生素、病毒唑加用激素静滴。
The author applied aminophylline, 654-2 treatment of bronchiolitis in infants and observed its efficacy compared with conventional hormones. 1 Clinical data 1995-1997 treatment of infantile bronchiolitis in 80 cases, 52 males and 28 females, ≤ 13 cases in February, ~ April 26 cases, ~ May in 41 cases, all cases have varying degrees of cough and asthma , 58 of them wheezing, cyanosis, dyspnea. 32 cases of fever. Pulmonary auscultation are heard wheeze, inspiratory period extended. 68 cases of different degrees of fine wet rales heard, all cases meet the diagnostic criteria for bronchiolitis. 80 cases were randomly divided into two groups. Control group 40 cases, treatment group 40 cases. The treatment group was treated with antibiotics, ribavirin plus aminophylline (2 ~ 4 mg · kg -1 / time) and 654-2 (0.2 ~ 0.3 mg · kg -1) L ~ (-1) glucose injection 50ml intravenous infusion of 1 to 2 times a day, 6d a course of treatment, the control group with conventional treatment, namely antibiotics, ribavirin plus hormone intravenous infusion.