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正常人在运动期间循环儿茶酚胺浓度增加。曾认为亚极量运动期间血浆肾上腺素与去甲肾上腺素浓度不能正常地增加是运动性哮喘的一个发病因素。作者选择6名正常人及6例哮喘患者作标准分级的最大运动试验,应用现代放身于酶测定法检测血浆儿茶酚胺浓度,以评估运动性哮喘患者交感肾上腺系统的反应住。通过氧耗量,运动时间、血乳酸浓度以及心率的测量,指示运动期间两组达到同样的劳动负荷,避免了以往亚极量运动研究两组未能达到同样负荷的缺陷。结果基础1秒种用力呼气量(FEV_1)平均值正常组4.1L,哮喘组3.7L。运动后哮喘组平均 FEV_1下
Normal circulation of catecholamines increased during exercise. It was thought that the abnormal increase of plasma epinephrine and norepinephrine during submaximal exercise was a contributing factor to exercise-induced asthma. The authors selected 6 normal subjects and 6 asthma patients as the maximal exercise test for standard grading. The plasma concentrations of catecholamines were separated by the enzyme-determination method in order to assess the response of the sympathetic adrenal system in patients with exercise-induced asthma. The measurement of oxygen consumption, exercise time, blood lactic acid concentration and heart rate indicated that the two groups reached the same labor load during exercise, avoiding the defects that the two groups failed to reach the same load in the past submaximal exercise study. Results Based on 1 second forced expiratory volume (FEV_1), the mean was 4.1L in the normal group and 3.7L in the asthma group. After exercise, the average asthma group FEV_1