为探讨棉酚是否作用于支持细胞而间接破坏生精细胞或通过损伤血睾屏障干扰曲细精管内微环境而导致生精过程终止,本实验采用辣根过氧化酶(Horseradish peroxidase)、硝酸镧(Lauthanum nitrate)及氯化锂(Lithium chloride)追踪观察成年大鼠服棉酚后血睾屏障的变化。结果表明,棉酚在具有明显抗生育作用下并未引起血睾屏障通透性损伤。似 In order to investigate whether gossypol acts on supporting cells and indirectly destroys spermatogenic cells or interferes with the microenvironment of seminiferous tubules by damaging blood-and-testis barrier, the process of spermatogenesis is terminated. Horseradish peroxidase, lanthanum nitrate (Lauthanum nitrate) and lithium chloride (Lithium chloride) follow-up observation of adult rat gossypol after blood testis barrier changes. The results show that gossypol has obvious resistance to fertility did not cause the blood-testis barrier permeability damage. like