研究内分泌学与免疫学的关系从第二次世界大战后到五十年代发展很快。这一方面要归因于类固醇化学的进步,各种类固醇激素的生物学功能得到深入认识。在此期间最有代表性的是H.Selye提出的应激理论(Stress theory),即基于肾上腺皮质抽提物引起胸腺淋巴组织萎缩说明内分泌对免疫反应的影响。1952年美国Dougherty发表了《激素对淋巴组织的作用》一文,提出了激素对淋巴组织 The study of the relationship between endocrinology and immunology developed rapidly from the second world war to the fifties. This is attributed in part to advances in steroid chemistry, with the understanding of the biological functions of various steroid hormones. The most representative of this period is the stress theory proposed by H. Selye, which shows the effect of endocrine on the immune response based on the atrophy of the adrenal cortex causing thymic lymphoid tissue. The United States in 1952 Dougherty published “the role of hormones on lymphoid tissue,” a text, proposed hormone on lymphoid tissue