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目的应用PET脑功能自动提取法研究18F-FDG PET显像受储尿刺激影响的脑解剖功能区。方法对25例正常人储尿和未储尿状态下分别进行18F-FDG PET/CT脑显像,应用脑功能自动提取法对比分析储尿前后18F-FDG脑显像的代谢变化,分析受储尿刺激影响的脑解剖功能核团。结果共22个脑解剖功能核团的代谢差异有统计学意义(P<0.05),其中双侧楔叶、左侧下枕回、左侧额中回、双侧额下回、双侧Brodmann17区、双侧Brodmann18区、双侧腹前核、右侧中央后回等13个核团代谢增高,同时左侧尾状核、双侧外侧核、左侧颞下回、左侧海马旁回、双侧胼胝体、左侧海马、左侧下丘脑等9个核团代谢降低。结论储尿刺激影响部分脑功能区代谢增高的同时使部分脑功能区代谢减低。18F-FDG PET/CT脑显像为临床研究泌尿中枢提供了功能-解剖学参考和重要的影像学方法。
Objective To study the brain anatomical functional areas affected by storage urine stimulation in 18F-FDG PET imaging by PET brain function automatic extraction method. Methods 18F-FDG PET / CT scintigraphy was performed on 25 normal individuals with and without urine storage. The metabolic changes of 18F-FDG brain imaging before and after storage were analyzed by automatic brain function extraction method. Urinary stimulation affects brain anatomical nuclei. Results A total of 22 brain anatomical functional groups metabolic differences were statistically significant (P <0.05), including bilateral wedge leaves, left lower back, left frontal gyrus, bilateral inferior frontal gyrus, bilateral Brodmann 17 , Bilateral Brodmann 18 zone, bilateral ventral prefrontal nucleus, right central back and other 13 nuclei increased metabolism, while the left caudate nucleus, bilateral lateral nucleus, left inferior temporal gyrus, left parahippocampal gyrus, double Side corpus callosum, left hippocampus, left hypothalamus and other nine nuclei decreased metabolism. Conclusions Storage urine stimulation can affect the metabolism of some brain functional areas and decrease the metabolism of some brain functional areas. 18F-FDG PET / CT brain imaging provides a functional, anatomical reference and an important imaging modality for the clinical study of the urinary tract.