本文报道了聚氧乙烯木醣醇酐单硬脂酸酯对大鼠致畸试验结果。剂量分别为750、1500和7500mg/kg时,该化学物对孕鼠体重增长无抑制作用,不影响胎仔存活及发育,也不引起胎仔外观、内脏及骨骼畸形,因此可以认为该化学物无胚胎毒性及致畸性。 This article reports the results of teratogenicity test of polyoxyethylene xylitol monostearate in rats. At doses of 750, 1500, and 7500 mg/kg, the chemical had no inhibitory effect on body weight gain in pregnant rats, did not affect fetal survival and development, and did not cause fetal appearance, visceral and skeletal deformities, so the chemical can be considered embryo-free Toxicity and teratogenicity.