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Objective: To investigate the therapeutic effects of stereotactic radiotherapy for retroperitoneal metastatic tumor.Methods: From August 1997 to October 2004,44 patients with retroperitoneal metastatic tumors were treated with stereotactic radiotherapy.The planning target volume was encompassed by 90%-95% isodose line.Fractional dose was from 6 Gy to 8 Gy,and they were treated 2-3 times per-week and 4-8 times in all.The total radiation doses of PTV were from 32 Gy to 48 Gy.Results: After the radiotherapy,the pain was obviously relieved in 81.8% patients.Three months after completion of radiotherapy passed and then,abdominal CT was performed to evaluate the results.The whole effective rate was 81.8% [CR 27.7% (12/44)and PR 54.5% (24/44)],and six months after radiotherapy,CR was 27.7% (12/44) and PR was 59.1% (26/44).The middle survival time was 12 months.Conclusion: It is suggested that stereotactic radiotherapy for retroperitoneal metastatic tumor is a safe and effective method.