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实验同步记录了豚鼠门静脉的自发活动和物（(86)Rb＋）流出速度。结果表明，K(ATP)开放剂罗卡林（Cromakalim，Cro）（1～10μmol／L）取消豚鼠门静脉的自发活动，增加(86)Rb＋的流出速度。内皮素-1（ET-1）（30nmol／L）增强豚鼠门静脉的自发活动，取消Cro增加(86)Rb+流出速度的作用。实验结果提示，ET-1对K(ATP)有一定的阻滞作用。
The spontaneous activity of the guinea pig portal vein and the (86) Rb + efflux rate were recorded simultaneously. The results showed that the spontaneous activity of guinea pig’s portal vein was abolished by Cromakalim (K) (1 ~ 10μmol / L), which increased the rate of (86) Rb + efflux. Endothelin-1 (ET-1) (30 nmol / L) increased spontaneous portal activity in guinea pigs and abolished the effect of Cro (86) Rb + efflux. The experimental results suggest that ET-1 has a certain block effect on K (ATP).