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目的 :探讨枢复宁和氟哌利多在妇科手术中的抗呕吐作用。方法 :选取妇科腹部手术患者60例。随机分为用药组30例在切皮时给以枢复宁4mg(溶于生理盐水20ml)与氟哌利多2 5mg 静脉注射 ;对照组30例 ,用0 9 %盐水10ml静脉注射。观察用药后抗恶心呕吐的效果 ,注药前和注药后5、10分钟记录平均动脉压 (MAP)、呼吸频率 (RF)、心率 (HR)和经皮血氧饱和度(SpO2)。结果 :用药组恶心呕吐发生率明显低于对照组 ,且MAP、SpO2、HR和RF无显著改变。结论 :枢复宁和氟哌利多合用能产生协同作用 ,更有效地降低妇科手术中的恶心呕吐发生率。
Objective: To investigate the anti-vomiting effect of pivotal and droperidol in gynecological surgery. Methods: Sixty cases of gynecological abdominal surgery were selected. Randomly divided into medication group 30 cases in the skin when given to Zu Fu Ning 4mg (dissolved in saline 20ml) and droperidol 25mg intravenous injection; control group of 30 patients with 0.9% saline 10ml intravenous injection. The anti-nausea and vomiting effects were observed. Mean arterial pressure (MAP), respiratory rate (RF), heart rate (HR) and percutaneous oxygen saturation (SpO2) were recorded before drug injection and at 5 and 10 minutes after drug injection. Results: The incidence of nausea and vomiting in the medication group was significantly lower than that in the control group, with no significant changes in MAP, SpO2, HR and RF. Conclusion: Combination of Shufuning and droperidol can produce synergetic effect and reduce the incidence of nausea and vomiting more effectively in gynecological surgery.