乳腺癌是威胁全世界妇女健康的主要疾病之一。近些年乳腺癌发病率呈逐年上升趋势,而且发病高峰提前;虽然针对乳腺癌的综合治疗已使其五年生存率有所提高,但是乳腺癌患者发生远处转移仍是影响其预后的重要因素之一。新近分子生物学研究表明:肿瘤细胞的某些基因活性改变及其表达 Breast cancer is one of the major diseases that threaten the health of women throughout the world. In recent years, the incidence of breast cancer showed an upward trend year by year, and the peak incidence of early; although the comprehensive treatment of breast cancer has made its five-year survival rate increased, but the occurrence of distant metastasis of breast cancer patients is still an important prognostic impact One of the factors. Recent molecular biology studies have shown that certain gene activity of tumor cells changes and its expression