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长链非编码RNA(lncRNA)是近年来肿瘤领域的研究热点,其数量众多,种类多样,功能多变,已被发现在机体多种病理生理过程中发挥重要的调控作用,且其功能失调与肿瘤的发生发展密切相关。目前已发现的lncRNA仅仅只是冰山一角,人们对lncRNA的研究尚在起步阶段,诸多功能和作用机制尚不明确。本文现综述lncRNA在卵巢癌、宫颈癌及子宫内膜癌等妇科常见恶性肿瘤中的作用机制和研究新进展。
Long-chain non-coding RNA (lncRNA) is a hot topic in the field of oncology in recent years. The large number, variety and variety of functions have been found to play an important regulatory role in many pathophysiological processes of the body, and its dysfunction and Tumor occurrence and development are closely related. The currently discovered lncRNA is just the tip of the iceberg, people are still at the initial stage of research on lncRNA, many functions and mechanism of action is not yet clear. This article reviews the lncRNA in ovarian cancer, cervical cancer and endometrial cancer and other gynecological common malignant tumors in the mechanism and research progress.