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目的探讨去氧孕烯炔雌醇治疗青春期功能性子宫出血(青春期功血)的临床疗效。方法选择2014年1月—2015年1月无锡市第二人民医院收治的50例青春期功血患者,采用随机数字表法将患者分为观察组(25例)和对照组(25例)。对照组给予黄体酮胶囊治疗,观察组给予去氧孕烯炔雌醇治疗,比较两组临床疗效、控制止血时间、完全止血时间和出血量、不良反应发生情况。结果观察组总有效率为100.00%,高于对照组的72.00%,差异有统计学意义(P<0.05)。观察组控制止血时间、完全止血时间短于对照组,出血量少于对照组,差异有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论去氧孕烯炔雌醇治疗青春期功血具有较好的临床疗效,可显著缩短控制止血时间、完全止血时间,减少出血量,不良反应少。
Objective To investigate the clinical efficacy of desogestrel ethinyl estradiol in the treatment of adolescent dysfunctional uterine bleeding (adolescent dysfunctional uterine bleeding). Methods Fifty patients with adolescent dysfunctional uterine bleeding treated in Wuxi Second People’s Hospital from January 2014 to January 2015 were randomly divided into observation group (25 cases) and control group (25 cases). The control group was treated with progesterone capsules. The observation group was treated with desogestrel ethinylestradiol. The clinical curative effect, the control of hemostasis time, the complete bleeding time, the amount of bleeding and the adverse reactions were compared. Results The total effective rate in observation group was 100.00%, which was higher than that in control group (72.00%), the difference was statistically significant (P <0.05). The observation group controlled bleeding time, complete bleeding time shorter than the control group, bleeding less than the control group, the difference was statistically significant (P <0.05). The incidence of adverse reactions in the two groups, the difference was not statistically significant (P> 0.05). CONCLUSION: Desopregnone ethinyl estradiol has good clinical efficacy in treating adolescent dysfunctional uterine bleeding, which can significantly shorten the time of hemostasis control, completely stop the bleeding, reduce the amount of bleeding and reduce the adverse reactions.