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乙型肝炎病毒的感染可发展为慢性持续性肝炎,慢性活动性肝炎、肝硬化,肝癌等慢性肝病。成人急性感染后变为持续性感染的占5～15％,在某些地区,如果幼年发生感染则持续性感染可高达9O％以上。据保守的估计,全世界有两亿以上乙型肝炎病毒携带者(约占世界人口的5％),因此需对高危人群进行乙型肝炎的免疫接种。此外,某些地区乙型肝炎病毒的高感染率及围产期传播也
Hepatitis B virus infection can develop chronic persistent hepatitis, chronic active hepatitis, cirrhosis, liver cancer and other chronic liver diseases. Adult acute infections become persistent infections accounted for 5 to 15%, in some areas, if the infection occurred in juvenile persistent infection can be as high as 9O%. According to conservative estimates, there are more than 200 million carriers of hepatitis B virus in the world (about 5% of the world’s population), so hepatitis B immunization is needed in high-risk groups. In addition, the high prevalence of hepatitis B virus infection and perinatal transmission in some areas also