To clarify the length and volume reduction of seminal vesicles (SVs) after neo-adjuvant hormonal therapy (NHT), in order to help contour the optimal SV included into high-dose clinical target volume (CTV) for radiotherapy in intermediate- and high-risk patients.
Methods:MR images both before and after NHT (5.3 ± 2.2 months) were collected from thirty-one patients with cT2-4N0M0 prostate cancer. SV volume was measured in axial T1WI, while SV length was obtained in a reconstructed oblique coronary plane through its long axial from a 3D sequence.
Results:SVs showed evident reduction both in length and volume (length: median 12.1%, range 4.0%–28.0%; volume: median 39.9%, range 9.4%–66.2%). For SVs with and without MR detected involvement, length shortening were (16.7 ± 4.8)% and (11.1 ± 4.4)% (P