Radioresistance相关论文
PIG3 downregulation enhances the radiosensitivity of NSCLC cells by promoting G2/M cell cycle arrest
Objective:Toinvestigatethemechanismofp53-inducedgene3(PIG3)-regulationofradioresistanceinhumannon-smallcelllungcancer(NS......
Radioresistance of chordoma cells associates with ATM/ATR pathway,in which RAD51 serves as an import
Surgery followed by radiotherapy is the standard treatment for chordomas that are rare but low-grade bone cancer arisen ......
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Objective Esophageal cancer ranks sixth for cancer related mortality globally.Radiation therapy is an effective method i......
miR-320a suppresses cell growth and enhances the sensitivity of the radioresistant lung adenocarcino
Radiotherapy is a major treatment measure for lung cancer therapy.However,acquired radioresistance of tumor cells during......
Rescue effects in radiobiology:unirradiated bystander cells assist irradiated cells through intercel
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The influence of cell cycle alteration on radiosensitivity in a radioresistant lung cancer cell line
Cancer patients often suffer from local tumor recurrence after radiation therapy.Cell cycle, an intricate sequence of ev......
Integrated analysis of differential miRNA and mRNA Expression Profiles in Human Radioresistant and R
To identify miRNAs and genes involved in NPC radioresistance,and explore the underlying mechanisms in the development of......
Purpose:This study was to investigated whether BRCC3 can be a prognostic marker for nasopharyngeal carcinoma and its pos......
Background:Esophageal cancer (EC) is one of the most aggressive malignant tumors, ranking eighth by global morbidity and......
HYDROGEN SULFIDE CONTRIBUTES TO RADIORESISTANCE AND THE SUPPRESSION OF RADIATION-INDUCED BYSTANDER E
Growing evidence has demonstrated that, as an endogenous signaling gasotransmitter,hydrogen sulfide (H2S) plays an impor......
Radioresistance remains the major obstacle to the treatment success of human cervical cancer.The present study was aimed......
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Identification of differential gene expression profiles of radioresistant lung cancer cell line esta
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肿瘤相关巨噬细胞（TAMs）与肿瘤的发生、发展、转移和复发密切相关。TAMs可根据表型及功能的不同分为M1型和M2型，分别与抗肿瘤免疫和促......
核转录因子红细胞系-2p45 （NF-E2）相关因子-2 (nuclear factor erythroid-2p45-related factor2，Nrf2)介导的细胞适应性氧化应激反应......
目的 放疗抵抗是食道癌等多种肿瘤放射治疗中的难题,许多文献报道CDC25c与肿瘤的演进及放疗抵抗密切相关,本实验旨在探讨分裂周期......
Hypoxia-induced Autophagy Contributes to Radioresistance via c-Jun-mediated Beclin1 Expression in Lu
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目的 建立肺癌细胞系A549的放射抗拒模型并探讨放射抗拒的机制.方法 应用两种方案对非小细胞肺癌A549细胞系进行X射线照射:一组照......
Identification of differential gene expression profiles of radioresistant lung cancer cell line esta
Background Radiotherapy plays a critical role in the management of non-small cell lung cancer (NSCLC). This study was co......
目的：探讨自噬对人肺腺癌细胞放疗敏感性的影响。方法采用透射电镜和荧光显微镜检测亲本人肺腺癌细胞SPC?A1和耐药细胞SPC?A1／DTX放......
目的体外建立非小细胞肺癌A549放疗抵抗模型,为进一步研究放疗抵抗的机制和治疗提供实验基础。方法摸索接种细胞数量及诱导照射剂......
Attenuated LKB1-SIK1 signaling promotes epithelial-mesenchymal transition andradioresistance ofnon-s
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Background and Objective: The mRNA levels of 59 genes, detected by cDNA micrearray, were up-regulated in the radioresist......
目的 研究具有不同放射抗拒性的人鼻咽癌细胞株CNE-2R与CNE-2的基因表达谱差异,筛选与鼻咽癌放射抗拒相关的基因信号通路.方法 验......
目的 比较食管癌放射抵抗细胞株与其亲本细胞microRNA表达谱的差异.方法 应用Agilent human miRNA芯片检测人食管癌耐放射细胞株KY......
目的 应用蛋白质相互作用网络图,寻找鼻咽癌放射抗拒相关的分子标志物,探讨鼻咽癌放射抗拒机制.方法 应用全基因组表达谱芯片,初步......
目的 探讨人脑胶质瘤干细胞SU2对辐射的耐受性及可能机制. 方法 U251细胞常规培养,SU2细胞分别在无血清DMEM/F12培养基、含10％胎牛......
目的分离、筛选、鉴定人鼻咽癌CNE-2及放射耐受CNE-2R的肿瘤干细胞。方法免疫磁珠技术分选CNE-2及CNE-2R中鼻咽癌CD133＋干细胞,分别......
Reduced radiosensitivity of lung cancer cells represents a pivotal obstacle in clinical oncology. The hypoxia-inducible ......
和全文的逐步筛选,最终纳入104篇符合入选标准的文献。结果与结论:乏氧微环境抑制缺氧诱导因子1α的降解,增多的缺氧诱导因子1α可......
目的探讨Beclin1基因对鼻咽癌细胞放疗抵抗的影响。方法Western blotting法检测CNE2、6-10B及其放疗抵抗细胞CNE2-Rs、6-10BRs中Be......
[摘要] 目的 研究环氧化酶-2与喉癌对放疗抗拒之间的关系，改善喉癌患者的生存率。 方法 选取122例早期喉癌患者，其中包括了61例放疗......
目的探讨利血生（西药）对X射线辐射损伤大鼠骨髓造血功能和免疫功能的影响。方法建立模型：给予大鼠剂量为4Gy、剂量率为2Gy／min的X射线......
AIM:To investigate the association between nuclearβ-catenin overexpression in rectal adenocarcinoma and radioresistance......
目的：研究姜黄素类似物B67对鼻咽癌（NPC）辐射抗拒细胞（CNE-2R）活性和增殖的作用,及其对细胞周期和凋亡的影响。方法：采用MTT和平板克隆形......
目的：探讨阿司匹林诱导同源不同辐射抗拒能力鼻咽癌细胞株CNE2R/CNE2凋亡的作用及其机制。方法：采用MTT法、流式细胞术和Western blo......
目的：研究硒蛋氨酸对食管癌放射抗拒细胞药物耐受性的影响。方法：以食管癌EC9706细胞为研究对象,建立放射抗拒的食管癌EC9706细胞株E......
目的：研究电离辐射能否导致人结肠癌细胞系HT-29中信号转导子与转录活化子6（STAT6）蛋白活化，从而探讨肿瘤出现放射抗拒的可能机制。方......
A1-5是一株典型的温度敏感的p53^val135细胞系，许多实验室用它来研究p53的功能，我们首次报道了A1-5细胞表现出非常强的抗辐射性并伴......
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Non-small cell lung cancer (NSCLC) accounts for 85% of lung cancer, which is the leading cause of death in lung cancer p......
目的比较不同放射敏感性鼻咽癌患者血清蛋白质表达差异,筛选出与鼻咽癌放射抗拒性相关的蛋白质。方法提取不同放射敏感性鼻咽癌患......
Constitutive Overexpression of Bcl-2, Survivin and ER Stress Chaperone GRP-78 Confers Intrinsic Radi
We present evidence here that abundantly expressed b-catenin-triggered NF-kB-dependent upregulation of inducible nitric ......
目的：通过上调Sonic Hedgehog（Shh）信号通路关键因子Gli1,探究Shh信号通路与食管癌细胞放射抗拒性及细胞周期的关系。方法：用过表达Gli......
Ionizing radiation (IR) is the most common treatment used to control localized primary prostate cancer (PC). However, fo......
报道了自１９５６年Ａｎｄｅｒｓｏｎ发现耐辐射异常球菌以来，国外在其生理生化和遗传学特性，特殊的细胞膜结构，各种诱变因素所致的ＤＮＡ损伤与其高效的修复机制和生......
