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为了解酸性牛神经肽1(ABNP1)对吸毒成瘾小鼠戒断后发作的治疗作用,连续10d给于实验小鼠盐酸吗啡使小鼠成瘾,停止给药后用吗啡拮抗剂纳洛酮催瘾,成瘾小鼠因戒断后发作从跳台上跳下。用ABNP1治疗成瘾小鼠(20g/kg,1次)。结果:使80%的成瘾小鼠不从跳台上跳下。结果表明:ABNP1能有效地治疗成瘾小鼠戒断后的发作
In order to understand the therapeutic effect of acidic bovine neuropeptide 1 (ABNP1) on withdrawal episodes after drug addiction in mice, the mice were addicted to morphine hydrochloride for 10 days in a row and were stopped after administration of morphine antagonist Na Loserone addiction, addiction Mice jumped off the platform as a result of withdrawal. Addicted with ABNP 1 mice (2 0g / kg, 1). Results: 80% of addicted mice do not jump off the platform. The results showed that: ABNP 1 can effectively treat addicted mice after the onset of withdrawal