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实验动物的脏器系数是指每100 g体重某一脏器所占的重量。它是亚急性和亚慢性毒性研究中常选择的观察点之一,它的变化可直接反映脏器是否有增生、充血、水肿或萎缩。Wistar大鼠是毒理学安全性评价和营养学实验研究中使用最多的动物,研究探讨其脏器系数随体重的变化规律,对正确
The organ coefficient of experimental animals refers to the weight of an organ per 100 g of body weight. It is one of the frequently-chosen observation points in the subacute and subchronic toxicology studies. Its change can directly reflect whether the organ has hyperplasia, congestion, edema or atrophy. Wistar rats are the most used animals in toxicology safety evaluation and nutrition experimental study to study the changes of their organ coefficient with body weight,