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通过对胃癌、胃溃疡间质肥大细胞的研究,探讨了这二类疾病中肥大细胞的意义。手术切除胃标本102例,经10%甲醛固定,HE染色和甲苯胺蓝染色,观察病变间质中肥大细胞的变化。结果:胃溃疡间质肥大细胞明显多于胃癌各组,高分化腺癌组多于低分化腺癌及未分化癌组。本文还就肥大细胞脱颗粒和异染颗粒等情况进行仔细观察,提示:肿瘤间质肥大细胞反应是机体拮抗肿瘤的一种形态学表现,间质肥大细胞的计数对胃的良恶性病变及胃癌恶性程度的判断有一定参考价值
Through the study of gastric cancer and gastric ulcer interstitial mast cells, the significance of mast cells in these two diseases was discussed. Surgical resection of 102 gastric specimens, fixed by 10% formaldehyde, HE staining and toluidine blue staining to observe the changes in interstitial mast cells. Results: Gastric mucosa interstitial mast cells were significantly more than those in gastric cancer group, well-differentiated adenocarcinoma group and poorly differentiated adenocarcinoma and undifferentiated carcinoma group. This article also males cell degranulation and heterophilic particles were observed carefully, suggesting that: tumor stromal mast cell response is a morphological manifestation of the body antagonistic tumors, interstitial mast cells count on benign and malignant gastric lesions and gastric cancer The judgment of the degree of malignancy has a certain reference value