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目的：分析１５３ＳｍＥＤＴＭＰ 治疗转移癌性骨痛的无效病例，以探讨影响治疗效果的可能因素。材料与方法：从３０个月内收集的１２４ 例中，比较有效及无效组的病种、治疗方法、临床情况、年龄、性别等因素，以ＳＡＳ 软件进行成组与多因素分析。结果：治疗无效的２２ 例中男性占９１ ％ （２０ 例） ，肺癌比重大（１３ 例） ，患者的临床情况、治疗方法、全组年龄分布等与治疗效果无明确关系；肿瘤类型和性别与治疗效果相关； 肺癌组的性别和年龄与治疗效果相关。结论：１５３ＳｍＥＤＴＭＰ 治疗时，肺癌，男性，和相对年轻者可能效果差。尽管机制不详，了解这些因素有助于估计疗效。
Objective: To analyze the 153Sm-EDTMP treatment of cancer metastatic bone pain ineffective cases to explore the possible factors affecting the treatment effect. Materials and Methods: Among the 124 cases collected within 30 months, the disease types, treatment methods, clinical conditions, ages, and genders of the effective and ineffective groups were compared and the SAS software was used for group and multivariate analysis. Results: Of the 22 patients who failed the treatment, 91% (20) were male, and the lung cancer ratio was significant (13). The clinical conditions, treatment methods, and age distribution of the entire group were not clearly related to the treatment effect; tumor type and gender The effect of treatment was related; The gender and age of the lung cancer group were related to the treatment effect. CONCLUSIONS: Lung cancer, males, and relatively young persons may have poor results when treated with 153Sm EDTMP. Although the mechanism is unknown, understanding these factors can help estimate the efficacy.