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目的:探讨骨髓细胞形态学变化特征在鉴别诊断骨髓增生异常综合征(MDS-RA)及巨幼红细胞性贫血(MA)中的意义。方法:骨髓片瑞氏染色,记数骨髓中有核细胞200个,并观察其形态。结果:(1)MDS的骨髓象除巨幼样变外,还有形态的异常。以淋巴样小巨核细胞最具有诊断意义。(2)巨幼红细胞性贫血三系血细胞的巨变程度比MDS-RA明显。结论:MDS-RA与MA细胞形态学既具有相似性,又具有各自不同特征。
Objective: To investigate the significance of morphological changes of bone marrow cells in differential diagnosis of myelodysplastic syndrome (MDS-RA) and megaloblastic anemia (MA). Methods: Bone marrow slices Wright’s stain, count 200 nucleated cells in bone marrow, and observe its morphology. Results: (1) In addition to the myeloid lesions of MDS, there are morphological abnormalities. Small lymphoid megakaryocytes with the most diagnostic significance. (2) Mesenchymal blood cells of megaloblastic anemia were more severe than those of MDS-RA. Conclusion: The morphology of MDS-RA and MA cells are both similar and have different characteristics.