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1980年1月在泰国Rayong行政区及其邻近村庄开始进行一次长期性的登革热流行病学研究,对在住户及学校的儿童以随机抽样法检血3,185人份,藉以评价当地人群对登革4个血清型的中和抗体水平;为了估计在一年里各个登革血清型的感染情况(登革血清阳转率),在1981年1月对一年级学生抽血检查;在此期间儿童因病入院治疗的,都抽血作登革病毒分离和双相血的抗体反应。
In January 1980, a long-term dengue epidemiological study was started in Rayong, Thailand and its neighboring villages. A total of 3,185 blood tests were performed on children in households and schools to assess the effect of local population on dengue 4 Serum neutralizing antibody levels; in order to estimate the infection status of each dengue serotype (dengue seroconversion rate) during the year, a first-year student blood test was performed in January 1981; Admission treatment, are blood for dengue virus isolation and biphasic blood antibody response.