本文报告7例急性炎性脱髓鞘多发性神经根神经病,临床表现为多数颅神经瘫伴有或不伴有共济失调和无反射、小脑性共济失调、类截瘫、感觉障碍和位置性低血压。这些特殊的临床变异型不只造成诊断上的困难,也使人疑及该病的病理过程是否累及中枢神经系统。本文病例提示该病的病理和免疫异常可表现为顿挫型、局限性和选择性过程。 This article reports 7 cases of acute inflammatory demyelinating polyneuropathy with clinical manifestations of most cranial nerve palsy with or without ataxia and reflex, cerebellar ataxia, paraplegia, sensory disturbances and positional Hypotension. These particular clinical variants not only cause diagnostic difficulties, but also make the question whether the pathological process of the disease affects the central nervous system. Our case suggests that the pathological and immunological abnormalities of the disease can be characterized as frustrated, localized and selective processes.