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目的:探讨小剂量红霉素治疗新生儿胃食道返流的疗效。方法:46例胃食道返流新生儿随机分为二组,对照组为“体位疗法/饮食疗法”治疗,治疗组为“体位疗法/饮食疗法/小剂量红霉素3~5mg/(kg·d)静滴”治疗。结果:两组患儿呕吐症状有统计学差异(P<0001)。结论:小剂量红霉素/体位疗法/饮食疗法治疗新生儿胃食道返流,疗效显著,值得临床应用。
Objective: To investigate the efficacy of low-dose erythromycin in the treatment of neonatal gastroesophageal reflux disease. Methods: 46 cases of neonates with gastroesophageal reflux were randomly divided into two groups. The control group was treated with “body position therapy / diet therapy”. The treatment group was “body position therapy / diet therapy / small dose erythromycin 3 ~ 5mg / D) intravenous infusion ”treatment. Results: There was a significant difference in the symptoms of vomiting between the two groups (P <0001). Conclusion: The low dose of erythromycin / body therapy / diet therapy for the treatment of neonatal gastroesophageal reflux has significant curative effect and is worthy of clinical application.