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无嘌呤 /无嘧啶核酸内切酶 (APE/Ref 1)是一种DNA修复酶 ,负责修复DNA上无嘌呤 /无嘧啶 (AP)位点 ,AP位点不完全修复会引起基因突变和遗传不稳定性。作者就短暂性全脑缺血时海马CA1区APE/Ref 1表达与细胞凋亡的关系进行了研究。选用体重 2 75~ 32 5克
The apurinic / apyrimidinic endonuclease (APE / Ref 1) is a DNA repair enzyme responsible for repairing apurinic / apyrimidinic (AP) sites on DNA. Incomplete AP site repair can cause genetic mutations and stability. The authors investigated the relationship between APE / Ref 1 expression in hippocampal CA1 region and apoptosis during transient global cerebral ischemia. Select the weight of 2 75 ~ 32 5 grams