动态轮廓眼压计监测LASIK手术前后眼压变化

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目的比较动态轮廓眼压计(DCT)、Goldmann压平式眼压计(GAT)及非接触式眼压计(NCT)测量接受准分子激光原位角膜磨镶术(LASIK)患者眼压值的差异。设计前瞻性临床试验研究。研究对象接受LASIK治疗的近视患者70例(140眼)。方法对上述患者于术前、术后1周,1、6个月用三种不同眼压计分别测量眼压,比较各时间点、各种眼压计之间的差异。同时记录手术前、后中央角膜厚度,取其两者差为角膜切削深度的值。主要指标眼压值(IOP)和角膜切削深度。结果术后1周,1、6个月DCT测量值(16.74±1.96mmHg、16.67±1.90mmHg、16.42±2.12mmHg)与其术前值(17.36±2.32mmHg)比较差异无统计学意义(F=1.346,P=0.06)。术后GAT和NCT测量值均呈下降趋势,与术前测量值比较差异有统计学意义(GAT:F=101.217,P=0.000;NCT:F=171.466,P=0.000),并且下降值与角膜切削深度成正相关关系(GAT:r=0.86,P=0.000;NCT:r=0.87,P=0.000),但术后三个时间段测量值比较差异无统计学意义(GAT术后三个时间点q值为0.216、0.677、0.461,P值分别为0.461、0.097、0.117;NCT术后三个时间点q值为0.215、0.585、0.370,P值分别为0.436、0.436、0.100)。结论LASIK术后GAT和NCT测量值明显下降,而DCT测量值无显著变化,其测量值较前两者更为可靠。(眼科,2007,16:344-347) Objective To compare the intraocular pressure (IOP) of patients undergoing laser in situ keratomileusis (LASIK) with dynamic contour tonometer (DCT), Goldmann flat tonometer (GAT) and non-contact tonometer difference. Design prospective clinical trial study. Seventy patients (140 eyes) with myopia treated with LASIK were included in this study. Methods The intraocular pressure (IOP) was measured before surgery, 1 week and 1, 6 months after operation in three kinds of different tonometer, and the differences among various time points and tonometers were compared. At the same time, the corneal thickness before and after surgery was recorded, and the difference between the two was the value of corneal cutting depth. The main indicators of intraocular pressure (IOP) and corneal cutting depth. Results There was no significant difference in the values ​​of DCT at 1 week, 1,6 months after operation (16.74 ± 1.96mmHg, 16.67 ± 1.90mmHg, 16.42 ± 2.12mmHg) and their preoperative values ​​(17.36 ± 2.32mmHg) (F = 1.346 , P = 0.06). The postoperative GAT and NCT values ​​showed a decreasing trend, which was significantly different from the preoperative values ​​(GAT: F = 101.217, P = 0.000; NCT: F = 171.466, P = 0.000) (GAT: r = 0.86, P = 0.000; NCT: r = 0.87, P = 0.000). However, there was no significant difference in the measured values ​​between the three time points after operation (three time points after GAT q values ​​were 0.216,0.677,0.461, P values ​​were 0.461,0.097,0.117; q values ​​were 0.215,0.585,0.370 three points after NCT, P values ​​were 0.436,0.436,0.100). Conclusions The GAT and NCT measurements decreased significantly after LASIK, while the DCT measurements showed no significant changes. The measured values ​​were more reliable than the former two. (Ophthalmology, 2007, 16: 344-347)
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