论文部分内容阅读
慢性粒细胞型白血病(以下简称慢粒)是最初命名为白血病的代表性疾患,首先由Craigie,Bennett及Virchow三人于1845年几乎同时分别通过临床、解剖及血液的显微镜检查结果而报道的,迄今已达182年之久。近年来由于细胞增殖动力学的阐明和化疗药物的研究,急性白血病治疗的进展极为显著,成人患者的完全缓解率可达60~80%,5年生存率迅速增加,尤其是小儿的急性淋巴细胞型白血病从完全缓解率及生存时间来看,甚至可以认为是能够治愈的疾患
Chronic myeloid leukemia (hereinafter referred to as CGRP) is a representative disorder originally named as leukemia. It was firstly reported by the clinical, anatomical and blood microscopic examination by Craigie, Bennett and Virchow in 1845 at about the same time. It has reached 182 years so far. In recent years, due to the clarification of cell proliferation kinetics and the study of chemotherapeutic drugs, the progress of acute leukemia treatment is extremely remarkable. The complete remission rate of adult patients can reach 60-80% and the 5-year survival rate rapidly increases, especially in children with acute lymphocytes Leukemia from complete remission rate and survival time point of view, can even be considered to be able to cure the disease