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目的探讨急性脑梗死合并感染对患者预后的影响。方法将96例经头颅 CT 证实的急性脑梗死患者依据其在住院期间是否合并感染,分为无感染组记录61例和合并感染组记录35例,记录两组病人的梗死灶面积、入院时体温及住院期间最高体温;在治疗前后不同时间检查周围血白细胞计数;并分别于入院时、治疗后1、3、7、21d 及出院后90 d 进行神经功能评分;于入院时、治疗后21d 及出院后90 d 行Barthel 指数评分。结果合并感染组入院时和住院期间最高体温均明显高于无感染组;梗死灶大于无感染组;治疗前、后不同时间点欧洲脑卒中分量表(ESS)积分和 Barthel 指数均明显低于无感染组,而周围血白细胞计数则明显高于无感染组。结论急性脑梗死合并感染的患者临床症状相对较重,预后较差,影响患者的神经功能恢复。
Objective To investigate the prognosis of patients with acute cerebral infarction complicated with infection. Methods A total of 96 patients with acute cerebral infarction confirmed by skull CT were divided into non-infected group and non-infected group according to whether they were co-infected during hospitalization. Among them, 61 cases were recorded as non-infected group and 35 cases were recorded as co-infected group. The infarct size, And the highest body temperature during hospitalization. Peripheral blood leukocyte counts were examined at different time points before and after treatment. Neurological scores were assessed at admission, 1, 3, 7, 21 days after treatment and 90 days after discharge. At admission, 21 days after treatment and Barthel index 90 days after discharge. Results The highest body temperature during hospital admission and hospitalization were significantly higher in infected patients than in non-infected patients. The infarct size was higher in non-infected patients than in non-infected patients. The scores of ESS and Barthel index in European infection group were significantly lower than those without infection Infection group, while the peripheral blood leukocyte count was significantly higher than the non-infected group. Conclusion The clinical symptoms of patients with acute cerebral infarction complicated by infection are relatively heavy with poor prognosis, affecting the recovery of neurological function in patients.