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[目的]探讨上海市浦东新区人群肺癌的危险因素。[方法]采用病例对照研究方法,收集浦东新区2008年1月1日至2009年6月30日期间新确诊的肺癌病例299例,按照居住区域、性别、年龄(±5岁)、民族进行1:1匹配。通过浦东新区疾病预防控制中心自行设计的问卷,对有关的暴露因素进行单因素和多因素Logistic回归分析。[结果]单因素分析发现20个暴露因素与肺癌的发生有关,多因素分析发现吸烟(OR=6.31,95%CI:3.88～0.24)为主要独立的危险因素;体质指数高(OR=0.87,95%CI:0.81～0.93)、口味辣(OR=0.53,95%CI:0.38～0.74)、食用豆油(OR=0.48,95%CI:0.31～0.74)、饮酒习惯(OR=0.28;95%CI:0.16～0.49)及每周锻炼(OR=0.74;95%CI:0.59～0.92)为可能的保护因素。[结论]肺癌的发生与多种环境危险因素的暴露有关,吸烟可能是浦东新区居民肺癌发生的主要危险因素。而体质指数高、口味辣、食用豆油、适量饮酒、每周锻炼有助于预防肺癌。
[Objective] To investigate the risk factors of lung cancer in Shanghai Pudong New Area. [Methods] A total of 299 new cases of lung cancer were collected from January 1, 2008 to June 30, 2009 in Pudong New Area from January 2008 to June 30, 2009 in accordance with the method of case-control study. The patients were divided into two groups according to their living area, sex, age : 1 match. Through the questionnaire designed by Pudong New Area CDC, univariate and multivariate Logistic regression analysis were conducted on the related exposure factors. [Results] Univariate analysis showed that 20 exposure factors were related to the occurrence of lung cancer. Multivariate analysis showed that smoking (OR = 6.31, 95% CI: 3.88-0.24) was the main independent risk factor. The body mass index was high (OR = 0.87, (OR = 0.48, 95% CI: 0.31-0.74), drinking habits (OR = 0.28; 95% CI: 0.81-0.93) CI: 0.16 ~ 0.49) and weekly exercise (OR = 0.74; 95% CI: 0.59 ~ 0.92) were possible protective factors. [Conclusion] The occurrence of lung cancer is related to the exposure of various environmental risk factors. Smoking may be the main risk factor of lung cancer in residents of Pudong New Area. The high body mass index, spicy taste, consumption of soybean oil, moderate drinking, weekly exercise helps prevent lung cancer.