Chronology is the basis for using lacustrine sediments to reconstruct the history of en-vironmental change. Radioactive-nuclides such as 14C, 210Pb and 137Cs dating are mainly used to establish the chronology for recent several ten thousand years. Because of being mixed with “dead carbon”, the measured 14C age is always older than the actual age which is recognized as “reservoir effect”. Cs is a kind of active metal element, and easy to migrate vertically in the sediment that leads to the error of the time marker. 210Pb dating should make sure to select CIC model or CRS model. On the Tibetan Plateau, most of the lakes are alkaline closed lake where Cs is more moveable in the sediment and the reservoir effect caused by “dead carbon” on 14C dating is stronger. Based on the analysis on results of 14C, 210Pb and 137Cs of the lacustrine sediments from Co Ngoin, central Tibetan Plateau, we use the simple regression method to re-calculate the 14C calendar ages, and establish the time sequence for cores CE-1 and CE-2 with result of 210Pb CRS model for the upper 35 cm and re-calculated 14C calendar age for sediments bellow 35 cm. Since 1400 cal. a BP, sedimentation inter-rupted for more than 1000 years. According to this time sequence, variations of environmental proxies confidently reflect the major climatic events in Holocene. Chronology is the basis for using lacustrine sediments to reconstruct the history of en-vironmental change. Radioactive-nuclides such as 14C, 210Pb and 137Cs dating are mainly used to establish the chronology for recent several ten thousand years. carbon “, the measured 14C age is always older than the actual age which is recognized as” reservoir effect “. Cs is a kind of active metal element, and easy to migrate vertically in the sediment that leads to the error of the time marker. 210Pb dating should make sure to select CIC model or CRS model. On the Tibetan Plateau, most of the lakes are alkaline closed lake where Cs is more moveable in the sediment and the reservoir effect caused by ”dead carbon" on 14C dating is stronger. Based on the analysis on results of 14C, 210Pb and 137Cs of the lacustrine sediments from Co Ngoin, central Tibetan Plateau, we use the simple regression method to re-calculate the 14C calendar ages, and establish the t ime sequence for cores CE-1 and CE-2 with result of 210Pb CRS model for the upper 35 cm and re-calculated 14C calendar age for sediments bellow 35 cm. Since 1400 cal. a BP, sedimentation inter-rupted for more than 1000 years. According to this time sequence, variations of environmental proxies confidently reflect the major climatic events in Holocene.