磷脂酶A_2(PLA_2)对于游离花生四烯酸的产生及其后环氧化酶和脂氧化酶的代谢途径至关重要。它可特异地催化许多甘油磷酸酯Sn-2位上的脂肪酸酯水解。根据结构和特异性。PLA_2可分为不同类型。I型PLA_2主要由胰腺产生并具有消化功能,Ⅱ型PLA_2存在于不同体液及某些蛇毒中。Ⅰ、Ⅱ型统称 Phospholipase A2 (PLA2) is crucial for the production of free arachidonic acid and its subsequent metabolic pathway for cyclooxygenase and lipoxygenase. It catalyzes the hydrolysis of many fatty acid esters at the Sn-2 position of many glycerophosphate esters. According to structure and specificity. PLA_2 can be divided into different types. Type I PLA 2 is mainly produced by the pancreas and has digestive function, type II PLA 2 is present in different body fluids and in some snake venom. Ⅰ, Ⅱ collectively