甲哌力复霉素(力复平)为一半合成抗生素,是目前评价较高的新的抗结核药物,国内已于1972年研制成功,1974年正式投入生产。近年来又进行了生产工艺改革,不少厂已采用经由力复噁嗪的新工艺来合成甲哌力复霉素。 在进行该新工艺路线的研究中,需要对其重要中间体力复噁嗪进行含量测定。试验发现该化合物有与其它力复霉素类不同的可见-紫外吸收光谱,可应用分光光度法测定该化合物的含量。 Metronidazole daunorubicin (Li Fu-ping) for the synthesis of antibiotics, is currently a high evaluation of new anti-TB drugs, the domestic has been successfully developed in 1972, officially put into production in 1974. In recent years, the production process has been carried out reform, many plants have adopted the new process through the synthesis of methoxypyrmethoxamivir. In the study of the new process route, we need to determine the content of its important intermediate. It has been found that this compound has a different visible-UV absorption spectrum than other fructocins, and the content of this compound can be determined spectrophotometrically.