目的 :对 40例单一视神经炎患者进行头部磁共振 ( MRI)检查及临床观察 ,证实部分视神经炎患者存在 CNS其他部位病损。方法 :头部 MRI采用自旋回波 ( SE) ,纵向射频重复时间为 30～ 5 0 0毫秒 ,全部病人进行了 1～ 6年的随访。结果 :16例脑 MRI有异常改变 ( 40 % )。经 1～ 6年的临床随访总共有 42 .5 %的单一视神经炎发展为临床确诊的多发性硬化 ( CDMS)。结论 :视神经炎经 MRI检查有多发性硬化的可能。同时经随访部分病人发展为 CDMS Objective: To investigate the head MRI and clinical observation of 40 patients with single optic neuritis, and to confirm the existence of lesions in other parts of CNS in some optic neuritis patients. Methods: Spin echo (SE) was used in the head MRI and the longitudinal RF repetition time was 30 ~ 500 ms. All the patients were followed up for 1-6 years. Results: 16 cases of brain MRI abnormalities (40%). A total of 42.5% of single optic neuritis progressed to clinically diagnosed multiple sclerosis (CDMS) after 1 to 6 years of clinical follow-up. Conclusion: Optic neuritis may have multiple sclerosis by MRI. At the same time some patients were followed up for the development of CDMS