精性肝病的演变规律是脂肪肝→酒精性肝炎→肝硬化。这几种病变往往可部分重叠，而且在很多病人身上可同时存在，但肝损害的关键性病变是终末肝微静脉周围的纤维化。 乙醇很容易从肠道吸收，其中 90％以上都在肝脏通过乙醇脱氢酶和一些微粒体的酶进行氧化代谢。长期大量饮酒会 The law of evolution of liver disease is fatty liver → alcoholic hepatitis → cirrhosis. These lesions are often partially overlapping and can occur in many patients at the same time, but the key lesion of liver damage is fibrosis around the terminal hepatic venules. Ethanol is easily absorbed from the gut, more than 90% of which are oxidatively metabolized in the liver by enzymes such as alcohol dehydrogenase and microsomes. Long-term heavy drinking party