目的　探讨糖皮质激素在严重急性呼吸综合征 (SARS)治疗中的作用。方法　对 2 0 0 3年 1月～ 5月在本院收治的 99例SARS患者的临床治疗进行回顾性分析。结果　糖皮质激素多采用早期、小剂量、短疗程方案。激素组 4 6例 ,非激素组 5 3例。激素组与非激素组年龄与性别构成比差异均无统计学意义(P >0 0 5 ) ;退热时间和肺部炎症吸收时间 ,激素组分别为 6 3±3 5天和 1 8 2± 7 8天 ,非激素组分别为 8 1± 3 2天和 2 1 7±8 9天 ,两组比较差异有统计学意义 (P <0 0 5 )。结论　早期、小剂量、短疗程使用糖皮质激素能明显缩短SARS的病程 ,加快肺部炎症的吸收 Objective To investigate the role of glucocorticoids in the treatment of severe acute respiratory syndrome (SARS). Methods The clinical data of 99 SARS patients admitted to our hospital from January to May in 2003 were analyzed retrospectively. Results glucocorticoid and more early, low-dose, short course of treatment options. 46 cases of hormone group, 53 cases of non-hormone group. There were no significant differences in age and sex ratio between the hormone group and the non-hormone group (P> 0.05). The time of fever relief and pulmonary inflammatory absorption time were 63.35 days and 182.2 78 days, the non-hormones were 81 ± 32 days and 21 7 ± 8 9 days, respectively. There was significant difference between the two groups (P <0.05). Conclusion Early, small dose, short course of treatment with glucocorticoids can significantly shorten the course of SARS and accelerate the absorption of lung inflammation