本文报道我院1971～1986年间206例金葡菌败血症的药敏试验结果及其与治疗的关系。发现金葡菌对头孢菌素,苯唑青霉素,庆大霉素、林可霉素及卡那霉素耐药菌株<40%;对青霉素G 和磺胺>88%。对氯霉素和红霉素的耐药菌株逐年增多。院内感染者耐药菌株一般较院外感染者为高。认为治疗期间金葡菌对抗生素的敏感性发生变化及合并有其它病原菌感染是治疗失败的原因之一。 This article reports 206 cases of Staphylococcus aureus sepsis in our hospital from 1971 to 1986 drug sensitivity test results and its relationship with treatment. Staphylococcus aureus was found to be <40% resistant to cephalosporins, oxacillin, gentamicin, lincomycin and kanamycin, and 88% to penicillin G and sulfonamides. Resistance to chloramphenicol and erythromycin strains increased year by year. Nosocomial infections resistant strains are generally higher than those outside the hospital. It is considered that the change of the sensitivity of S.aureus to antibiotics during treatment and the combination of other pathogens are one of the reasons for the failure of treatment.