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唇裂和(或)腭裂(CLP)是最常见的颅面畸形,CLP伴有其它部位畸形已有许多报道,有人报道伴随畸形的发生率可达44％～63％,常见有中枢神经系统、心脏、肌肉骨骼系统等。关于伴发颈椎异常的情况以往颇有争议,作者观察了468例CLP患者,对伴有颈椎异常的发生率及分布进行了分析。 468例均为美国两所大学腭裂诊所的患者,年龄7～18岁,(因为颈椎在7岁时才发育完全)。将患者分为4组:唇裂和(或)齿槽裂组,完全性单侧或双侧裂组,单纯腭裂组和软腭或粘膜下裂组。随机选择100例正畸治疗患者为对照组。结果表明,CLP患者颈椎异常发生率为22％。软腭及粘膜下裂组颈椎异常的发生率最高(45％),唇和(或)齿槽裂组的发生率与对照组相似,完全性单侧或双侧
Cleft lip and / or cleft palate (CLP) is the most common craniofacial deformity, CLP with other parts of the deformity has been reported, it was reported with the incidence of malformations up to 44% to 63%, common central nervous system, heart , Musculoskeletal system and so on. In the past, there were controversies regarding the presence of cervical abnormalities. The authors looked at 468 CLP patients and analyzed the incidence and distribution of cervical abnormalities. All 468 patients were in the cleft palate clinic at the United States between the ages of 7 and 18 years old (because the cervical spine developed completely at 7 years of age). Patients were divided into 4 groups: cleft lip and / or alveolar cleft, complete unilateral or bilateral cleft, simple cleft palate and soft palate or submucosa. 100 cases of orthodontic treatment were randomly selected as the control group. The results showed that CLP patients with cervical anomalous incidence of 22%. The incidence of cervical abnormalities was the highest in the soft palate and submucosa (45%), and the incidence of lip and / or alveolar cleft was similar to that in the control group, with complete unilateral or bilateral