原发性震颤是一种预后良好的家族性遗传性疾病,在临床上常误诊为巴金森氏综合征、肝豆状核变性、甲状腺机能亢进、小脑疾病以及神经官能症等。作者发现3上家系,现报告如下。家系1,先证者(Ⅰ_4),女,6岁,诉双手发生震颤20年左右,近年来加重,写字或持针缝衣时震颤更加明显,每当在众人面前讲话时,情绪紧张,发生语言震 Primary tremor is a familial inherited disease with a good prognosis. It is often clinically misdiagnosed as Parkinson’s syndrome, hepatolenticular degeneration, hyperthyroidism, cerebellar disease and neurosis. The author found 3 on the family, the report is as follows. Pedigree 1, proband (Ⅰ_4), female, 6 years old, v. Trembling hands complain about 20 years, aggravating in recent years, writing or holding a needle when sewing tremor more pronounced, whenever the speech in front of everyone, nervousness occurs Language shock